TGF-β-mediated sustained ERK1/2 activity promotes the inhibition of intracellular growth of Mycobacterium avium in epithelioid cells surrogates.

TGF-β-mediated sustained ERK1/2 activity promotes the inhibition of intracellular growth of Mycobacterium avium in epithelioid cells surrogates.

Transforming growth factor beta (TGF-β) has been implicated in the pathogenesis of several diseases including infection with intracellular pathogens such as the Mycobacterium avium complex. Infection of macrophages with M. avium induces TGF-β production and neutralization of this cytokine has been a...

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Bibliographic Details
Main Authors: Carolina L'Abbate, Ivone Cipriano, Elizabeth Cristina Pérez-Hurtado, Sylvia Cardoso Leão, Célia Regina Whitaker Carneiro, Joel Machado
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3120888?pdf=render

Internet

http://europepmc.org/articles/PMC3120888?pdf=render

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