Hydrolysis of Extracellular ATP by Vascular Smooth Muscle Cells Transdifferentiated into Chondrocytes Generates P<sub>i</sub> but Not PP<sub>i</sub>

Hydrolysis of Extracellular ATP by Vascular Smooth Muscle Cells Transdifferentiated into Chondrocytes Generates P<sub>i</sub> but Not PP<sub>i</sub>

(1) Background: Tissue non-specific alkaline phosphatase (TNAP) is suspected to induce atherosclerosis plaque calcification. TNAP, during physiological mineralization, hydrolyzes the mineralization inhibitor inorganic pyrophosphate (PP<sub>i</sub>). Since atherosclerosis plaques are char...

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Bibliographic Details
Main Authors: Rene Buchet, Camille Tribes, Valentine Rouaix, Bastien Doumèche, Michele Fiore, Yuqing Wu, David Magne, Saida Mebarek
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:International Journal of Molecular Sciences
Subjects:
ATP
alkaline phosphatase
aortic smooth muscle cell
calcification
chondrocyte
plaque calcification
Online Access:https://www.mdpi.com/1422-0067/22/6/2948

Internet

https://www.mdpi.com/1422-0067/22/6/2948

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