AMD1 upregulates hepatocellular carcinoma cells stemness by FTO mediated mRNA demethylation

Abstract Background S‐adenosylmethionine decarboxylase proenzyme (AMD1) is a key enzyme involved in the synthesis of spermine (SPM) and spermidine (SPD), which are associated with multifarious cellular processes. It is also found to be an oncogene in multiple cancers and a potential target for tumor...

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Bibliographic Details
Main Authors: Xinyu Bian, Dongmin Shi, Kailin Xing, Hongxin Zhou, Lili Lu, Dahai Yu, Weizhong Wu
Format: Article
Language:English
Published: Wiley 2021-03-01
Series:Clinical and Translational Medicine
Subjects:
FTO
Online Access:https://doi.org/10.1002/ctm2.352