CD4+ T Cells Play a Critical Role in Microbiota-Maintained Anti-HBV Immunity in a Mouse Model

CD4+ T Cells Play a Critical Role in Microbiota-Maintained Anti-HBV Immunity in a Mouse Model

The ability of the host to clear hepatitis B virus (HBV) is closely correlated to the establishment of commensal microbiota. However, how microbiota affects anti-HBV immunity is still unclear. Using a well-known hydrodynamical HBV transfection mouse model and treatment with antibiotics (Atb), we exp...

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Bibliographic Details
Main Authors: Tingxin Wu, Fenglei Li, Yongyan Chen, Haiming Wei, Zhigang Tian, Cheng Sun, Rui Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Immunology
Subjects:
hepatitis B virus
commensal microbiota
CD4+ T cell
anti-viral immunity
germinal center B cell
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00927/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.00927/full

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