NRFL-1, the C. elegans NHERF orthologue, interacts with amino acid transporter 6 (AAT-6) for age-dependent maintenance of AAT-6 on the membrane.

NRFL-1, the C. elegans NHERF orthologue, interacts with amino acid transporter 6 (AAT-6) for age-dependent maintenance of AAT-6 on the membrane.

The NHERF (Na(+)/H(+) exchanger regulatory factor) family has been proposed to play a key role in regulating transmembrane protein localization and retention at the plasma membrane. Due to the high homology between the family members, potential functional compensations have been a concern in sorting...

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Main Authors: Kohei Hagiwara, Shushi Nagamori, Yasuhiro M Umemura, Ryuichi Ohgaki, Hidekazu Tanaka, Daisuke Murata, Saya Nakagomi, Kazuko H Nomura, Eriko Kage-Nakadai, Shohei Mitani, Kazuya Nomura, Yoshikatsu Kanai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3419730?pdf=render

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http://europepmc.org/articles/PMC3419730?pdf=render

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