New insights into the cellular activities of Fndc5/Irisin and its signaling pathways

Abstract Fndc5, a well-defined myokine and also identified as an adipokine, has a critical role in modulation of metabolism and protection against obesity. These important functions are mediated by irisin, a secretory peptide produced from proteolytic processing of Fndc5. The other beneficial physio...

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Bibliographic Details
Main Authors: Farzaneh Rabiee, Liana Lachinani, Sarvenaz Ghaedi, Mohammad Hossein Nasr-Esfahani, Timothy L. Megraw, Kamran Ghaedi
Format: Article
Language:English
Published: BMC 2020-03-01
Series:Cell & Bioscience
Online Access:http://link.springer.com/article/10.1186/s13578-020-00413-3