On hepatitis C virus evolution: the interaction between virus and host towards treatment outcome.

BACKGROUND: Hepatitis C is a disease spread throughout the world. Hepatitis C virus (HCV), the etiological agent of this disease, is a single-stranded positive RNA virus. Its genome encodes a single precursor protein that yields ten proteins after processing. NS5A, one of the non-structural viral pr...

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Bibliographic Details
Main Authors: Cíntia Bittar, Ana Carolina Gomes Jardim, Lilian Hiromi Tomonari Yamasaki, Claudia Márcia Aparecida Carareto, João Renato Rebello Pinho, Philippe Lemey, Isabel Maria Vicente Guedes de Carvalho-Mello, Paula Rahal
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3636177?pdf=render