Blocking mineralocorticoid receptors prior to retrieval reduces contextual fear memory in mice.

BACKGROUND: Corticosteroid hormones regulate appraisal and consolidation of information via mineralocorticoid receptors (MRs) and glucocorticoid receptors (GRs) respectively. How activation of these receptors modulates retrieval of fearful information and the subsequent expression of fear is largely...

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Bibliographic Details
Main Authors: Ming Zhou, Merel Kindt, Marian Joëls, Harm J Krugers
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3192177?pdf=render