Challenges and Approaches to Genotyping Repetitive DNA

Challenges and Approaches to Genotyping Repetitive DNA

Individuals within a species can exhibit vast variation in copy number of repetitive DNA elements. This variation may contribute to complex traits such as lifespan and disease, yet it is only infrequently considered in genotype-phenotype associations. Although the possible importance of copy number...

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Bibliographic Details
Main Authors: Elizabeth A. Morton, Ashley N. Hall, Elizabeth Kwan, Calvin Mok, Konstantin Queitsch, Vivek Nandakumar, John Stamatoyannopoulos, Bonita J. Brewer, Robert Waterston, Christine Queitsch
Format: Article
Language:English
Published: Oxford University Press 2020-01-01
Series:G3: Genes, Genomes, Genetics
Subjects:
ribosomal dna
repetitive dna
whole genome sequencing
copy number variation
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.119.400771

Internet

http://g3journal.org/lookup/doi/10.1534/g3.119.400771

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