Hugl1 and Hugl2 in mammary epithelial cells: polarity, proliferation, and differentiation.

Loss of epithelial polarity is described as a hallmark of epithelial cancer. To determine the role of Hugl1 and Hugl2 expression in the breast, we investigated their localization in human mammary duct tissue and the effects of expression modulation in normal and cancer cell lines on polarity, prolif...

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Bibliographic Details
Main Authors: Atlantis Russ, Jeanne M V Louderbough, Daniela Zarnescu, Joyce A Schroeder
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3479147?pdf=render