The Hinge Region of Bovine Zona Pellucida Glycoprotein ZP3 Is Involved in the Formation of the Sperm-Binding Active ZP3/ZP4 Complex

The Hinge Region of Bovine Zona Pellucida Glycoprotein ZP3 Is Involved in the Formation of the Sperm-Binding Active ZP3/ZP4 Complex

The zona pellucida (ZP) surrounds the mammalian oocyte and mediates species-selective sperm-oocyte interactions. Bovine ZP consists of glycoproteins ZP2, ZP3, and ZP4. Neither ZP3 nor ZP4 alone shows inhibitory activity for the binding of sperm to the ZP; however, this activity is seen with the ZP3/...

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Bibliographic Details
Main Authors: Kaori Suzuki, Nanami Tatebe, Sayuri Kojima, Ayumi Hamano, Misaki Orita, Naoto Yonezawa
Format: Article
Language:English
Published: MDPI AG 2015-11-01
Series:Biomolecules
Subjects:
zona pellucida
fertilization
glycoprotein
baculovirus-Sf9 cell
Online Access:http://www.mdpi.com/2218-273X/5/4/3339

Internet

http://www.mdpi.com/2218-273X/5/4/3339

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