Long-term follow up after denosumab treatment for osteoporosis – rebound associated with hypercalcemia, parathyroid hyperplasia, severe bone mineral density loss, and multiple fractures: a case report

Long-term follow up after denosumab treatment for osteoporosis – rebound associated with hypercalcemia, parathyroid hyperplasia, severe bone mineral density loss, and multiple fractures: a case report

Abstract Background The rebound effect after stopping treatment with denosumab may be associated with rapid loss of the gains in bone mineral density achieved with treatment, high levels of bone remodeling markers, the occurrence of vertebral fractures, and even hypercalcemia. Case presentation A 64...

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Bibliographic Details
Main Authors: Yves Maugars, Pascale Guillot, Joëlle Glémarec, Jean-Marie Berthelot, Benoit Le Goff, Christelle Darrieutort-Laffite
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Journal of Medical Case Reports
Subjects:
Osteoporosis
Denosumab rebound
Fracture
Hypercalcemia
Hyperparathyroidism
Online Access:http://link.springer.com/article/10.1186/s13256-020-02401-0

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http://link.springer.com/article/10.1186/s13256-020-02401-0

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