Functional Coupling of Slack Channels and P2X3 Receptors Contributes to Neuropathic Pain Processing

Functional Coupling of Slack Channels and P2X3 Receptors Contributes to Neuropathic Pain Processing

The sodium-activated potassium channel Slack (K<sub>Na</sub>1.1, Slo2.2, or Kcnt1) is highly expressed in populations of sensory neurons, where it mediates the sodium-activated potassium current (I<sub>KNa</sub>) and modulates neuronal activity. Previous studies suggest that...

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Bibliographic Details
Main Authors: Ruirui Lu, Katharina Metzner, Fangyuan Zhou, Cathrin Flauaus, Annika Balzulat, Patrick Engel, Jonas Petersen, Rebekka Ehinger, Anne Bausch, Peter Ruth, Robert Lukowski, Achim Schmidtko
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:International Journal of Molecular Sciences
Subjects:
Slack
P2X3
dorsal root ganglia
neuropathic pain
mice
Online Access:https://www.mdpi.com/1422-0067/22/1/405

Internet

https://www.mdpi.com/1422-0067/22/1/405

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