Cell-Type Specific Development of the Hyperpolarization-Activated Current, Ih, in Prefrontal Cortical Neurons

H-current, also known as hyperpolarization-activated current (Ih), is an inward current generated by the hyperpolarization-activated cyclic nucleotide-gated (HCN) cation channels. Ih plays an essential role in regulating neuronal properties, synaptic integration and plasticity, and synchronous activ...

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Bibliographic Details
Main Authors: Sha-Sha Yang, Yan-Chun Li, Austin A. Coley, Linda A. Chamberlin, Ping Yu, Wen-Jun Gao
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Synaptic Neuroscience
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Online Access:http://journal.frontiersin.org/article/10.3389/fnsyn.2018.00007/full