Na/K Pump and Beyond: Na/K-ATPase as a Modulator of Apoptosis and Autophagy

Na/K Pump and Beyond: Na/K-ATPase as a Modulator of Apoptosis and Autophagy

Lung cancer is a leading cause of global cancer deaths. Na/K-ATPase has been studied as a target for cancer treatment. Cardiotonic steroids (CS) trigger intracellular signalling upon binding to Na/K-ATPase. Normal lung and tumour cells frequently express different pump isoforms. Thus, Na/K-ATPase is...

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Bibliographic Details
Main Authors: Cassiano Felippe Gonçalves-de-Albuquerque, Adriana Ribeiro Silva, Camila Ignácio da Silva, Hugo Caire Castro-Faria-Neto, Patrícia Burth
Format: Article
Language:English
Published: MDPI AG 2017-04-01
Series:Molecules
Subjects:
Na/K-ATPase
non-small cell lung cancer
cardiotonic steroids
apoptosis
autophagy
Online Access:http://www.mdpi.com/1420-3049/22/4/578

Internet

http://www.mdpi.com/1420-3049/22/4/578

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