Detection of suspicious interactions of spiking covariates in methylation data

Abstract Background In methylation analyses like epigenome-wide association studies, a high amount of biomarkers is tested for an association between the measured continuous outcome and different covariates. In the case of a continuous covariate like smoking pack years (SPY), a measure of lifetime e...

Full description

Bibliographic Details
Main Authors: Miriam Sieg, Gesa Richter, Arne S. Schaefer, Jochen Kruppa
Format: Article
Language:English
Published: BMC 2020-01-01
Series:BMC Bioinformatics
Subjects:
Online Access:https://doi.org/10.1186/s12859-020-3364-6