Detection of suspicious interactions of spiking covariates in methylation data
Abstract Background In methylation analyses like epigenome-wide association studies, a high amount of biomarkers is tested for an association between the measured continuous outcome and different covariates. In the case of a continuous covariate like smoking pack years (SPY), a measure of lifetime e...
Main Authors: | Miriam Sieg, Gesa Richter, Arne S. Schaefer, Jochen Kruppa |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-01-01
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Series: | BMC Bioinformatics |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12859-020-3364-6 |
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