Association of promoter methylation of VGF and PGP9.5 with ovarian cancer progression.

Association of promoter methylation of VGF and PGP9.5 with ovarian cancer progression.

PURPOSE:To elucidate the role of biological and clinical impact of aberrant promoter hypermethylation (PH) in ovarian cancer (OC). EXPERIMENTAL DESIGN:PH of PGP9.5, HIC1, AIM1, APC, PAK3, MGMT, KIF1A, CCNA1, ESR1, SSBP2, GSTP1, FKBP4 and VGF were assessed by quantitative methylation specific PCR (QM...

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Main Authors: Mariana Brait, Leonel Maldonado, Maartje G Noordhuis, Shahnaz Begum, Myriam Loyo, Maria Luana Poeta, Alvaro Barbosa, Vito M Fazio, Roberto Angioli, Carla Rabitti, Luigi Marchionni, Pauline de Graeff, Ate G J van der Zee, G Bea A Wisman, David Sidransky, Mohammad O Hoque
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3785492?pdf=render

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http://europepmc.org/articles/PMC3785492?pdf=render

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