Evaluation of genetically inactivated alpha toxin for protection in multiple mouse models of Staphylococcus aureus infection.

Staphylococcus aureus is a major human pathogen and a leading cause of nosocomial and community-acquired infections. Development of a vaccine against this pathogen is an important goal. While S. aureus protective antigens have been identified in the literature, the majority have only been tested in...

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Bibliographic Details
Main Authors: Rebecca A Brady, Christopher P Mocca, Ranjani Prabhakara, Roger D Plaut, Mark E Shirtliff, Tod J Merkel, Drusilla L Burns
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3639205?pdf=render