A developmental stage-specific switch from DAZL to BOLL occurs during fetal oogenesis in humans, but not mice.

The Deleted in Azoospermia gene family encodes three germ cell-specific RNA-binding proteins (DAZ, DAZL and BOLL) that are essential for gametogenesis in diverse species. Targeted disruption of Boll in mice causes male-specific spermiogenic defects, but females are apparently fertile. Overexpression...

Full description

Bibliographic Details
Main Authors: Jing He, Kayleigh Stewart, Hazel L Kinnell, Richard A Anderson, Andrew J Childs
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3783425?pdf=render