Role of cell-to-cell variability in activating a positive feedback antiviral response in human dendritic cells.

In the first few hours following Newcastle disease viral infection of human monocyte-derived dendritic cells, the induction of IFNB1 is extremely low and the secreted type I interferon response is below the limits of ELISA assay. However, many interferon-induced genes are activated at this time, for...

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Bibliographic Details
Main Authors: Jianzhong Hu, German Nudelman, Yishai Shimoni, Madhu Kumar, Yaomei Ding, Carolina López, Fernand Hayot, James G Wetmur, Stuart C Sealfon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-02-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3035661?pdf=render