Characterization of <i>Pseudomonas aeruginosa</i> Quorum Sensing Inhibitors from the Endophyte <i>Lasiodiplodia venezuelensis</i> and Evaluation of Their Antivirulence Effects by Metabolomics

Characterization of <i>Pseudomonas aeruginosa</i> Quorum Sensing Inhibitors from the Endophyte <i>Lasiodiplodia venezuelensis</i> and Evaluation of Their Antivirulence Effects by Metabolomics

The opportunistic pathogen <i>Pseudomonas aeruginosa</i> is one of the “critical priority pathogens” due to its multidrug resistance to a wide range of antibiotics. Its ability to invade and damage host tissues is due to the use of quorum sensing (QS) to collectively produce a plethora o...

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Bibliographic Details
Main Authors: Léonie Pellissier, Sara Leoni, Laurence Marcourt, Emerson Ferreira Queiroz, Nicole Lecoultre, Luis-Manuel Quiros-Guerrero, Morgane Barthélémy, Véronique Eparvier, Jérôme Chave, Didier Stien, Katia Gindro, Karl Perron, Jean-Luc Wolfender
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Microorganisms
Subjects:
natural products
quorum sensing inhibition
<i>Pseudomonas aeruginosa</i>
endophytic fungi
<i>Lasiodiplodia venezuelensis</i>
bio-guided fractionation
Online Access:https://www.mdpi.com/2076-2607/9/9/1807

Internet

https://www.mdpi.com/2076-2607/9/9/1807

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