Identification of Redox and Glucose-Dependent Txnip Protein Interactions

Thioredoxin-interacting protein (Txnip) acts as a negative regulator of thioredoxin function and is a critical modulator of several diseases including, but not limited to, diabetes, ischemia-reperfusion cardiac injury, and carcinogenesis. Therefore, Txnip has become an attractive therapeutic target...

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Bibliographic Details
Main Authors: Benjamin J. Forred, Skyla Neuharth, Dae In Kim, Michael W. Amolins, Khatereh Motamedchaboki, Kyle J. Roux, Peter F. Vitiello
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2016/5829063