Targeting the Epidermal Growth Factor Receptor in Addition to Chemotherapy in Patients with Advanced Pancreatic Cancer: A Systematic Review and Meta-Analysis

Overexpression of epidermal growth factor receptors (EGFR) occurs in >90% of pancreatic ductal adenocarcinomas (PDACs) and is associated with a poorer prognosis. A systematic review of electronic databases identified studies exploring the addition of EGFR-targeted treatment to chemotherapy in...

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Bibliographic Details
Main Authors: Jaseela Chiramel, Alison C. Backen, Rille Pihlak, Angela Lamarca, Melissa Frizziero, Noor-ul-Ain Tariq, Richard A. Hubner, Juan W. Valle, Eitan Amir, Mairéad G. McNamara
Format: Article
Language:English
Published: MDPI AG 2017-04-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:http://www.mdpi.com/1422-0067/18/5/909