Mechanochemistry of von Willebrand factor

Von Willebrand factor (VWF), a blood multimeric protein with a very high molecular weight, plays a crucial role in the primary haemostasis, the physiological process characterized by the adhesion of blood platelets to the injured vessel wall. Hydrodynamic forces are responsible for extensive conform...

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Bibliographic Details
Main Authors: Lancellotti Stefano, Sacco Monica, Basso Maria, Cristofaro Raimondo De
Format: Article
Language:English
Published: De Gruyter 2019-11-01
Series:Biomolecular Concepts
Subjects:
Online Access:https://doi.org/10.1515/bmc-2019-0022