Partners in crime: the TGFβ and MAPK pathways in cancer progression

<p>Abstract</p> <p>The TGFβ and Ras-MAPK pathways play critical roles in cell development and cell cycle regulation, as well as in tumor formation and metastasis. In the absence of cellular transformation, these pathways operate in opposition to one another, where TGFβ maintains an...

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Bibliographic Details
Main Authors: Chapnick Douglas A, Warner Lisa, Bernet Jennifer, Rao Timsi, Liu Xuedong
Format: Article
Language:English
Published: BMC 2011-12-01
Series:Cell & Bioscience
Subjects:
ERK
MEK
Ras
Online Access:http://www.cellandbioscience.com/content/1/1/42