Inhibition of LTA4H by bestatin in human and mouse colorectal cancerResearch in context

Background: Our preclinical data showed that the leukotriene A4 hydrolase (LTA4H) pathway plays a role in colorectal cancer (CRC). High expression of LTA4H and leukotriene B4 receptor type 1 (BLT1) were also associated with CRC survival probability. Clinical samples were evaluated to determine wheth...

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Bibliographic Details
Main Authors: Simin Zhao, Ke Yao, Dan Li, Kangdong Liu, Guoguo Jin, Mingyang Yan, Qiong Wu, Hanyong Chen, Seung Ho Shin, Ruihua Bai, Gangcheng Wang, Ann M. Bode, Ziming Dong, Zhiping Guo, Zigang Dong
Format: Article
Language:English
Published: Elsevier 2019-06-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396419303093