Development of a UPLC-TQ/MS Approach for the Determination of Eleven Bioactive Components in Haizao Yuhu Decoction Plus-Minus Haizao and Gancao Drug Combination after Oral Administration in a Rat Model of Hypothyroidism

Development of a UPLC-TQ/MS Approach for the Determination of Eleven Bioactive Components in Haizao Yuhu Decoction Plus-Minus Haizao and Gancao Drug Combination after Oral Administration in a Rat Model of Hypothyroidism

Haizao Yuhu Decoction (HYD) has been used for approximately 500 years and is well-known in Traditional Chinese Medicine for its efficacy in the treatment of thyroid-related diseases. In this study, a rapid liquid chromatography-tandem mass spectrometry method was developed for the determination of l...

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Bibliographic Details
Main Authors: Yingchang Ma, Yang Zhang, Yuanjuan Zhai, Zhenhua Zhu, Ying Pan, Dawei Qian, Shulan Su, Xinsheng Fan, Jinao Duan
Format: Article
Language:English
Published: MDPI AG 2016-12-01
Series:Molecules
Subjects:
Haizao Yuhu Decoction
hypothyroidism
multiple components
pharmacokinetic differences
UPLC-TQ/MS
Online Access:http://www.mdpi.com/1420-3049/22/1/7

Internet

http://www.mdpi.com/1420-3049/22/1/7

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