Prevalence of BRCA1 and BRCA2 gene mutations in families with medium and high risk of breast and ovarian cancer in Brazil

Prevalence of BRCA1 and BRCA2 gene mutations in families with medium and high risk of breast and ovarian cancer in Brazil

Of all malignant neoplasias affecting women, breast cancer has the highest incidence rate in Brazil. The objective of the present study was to determine the frequency of genetic modifications in families with medium and high risk for breast and ovarian cancer from different regions of Brazil. An exp...

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Bibliographic Details
Main Authors: V.F. Esteves, L.C.S. Thuler, L.C. Amêndola, R.J. Koifman, S. Koifman, P.P. Frankel, R.J.S. Vieira
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2009-05-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Breast cancer
BRCA1
BRCA2
Mutations
Brazil
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009000500009

Internet

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009000500009

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