Investigation of forced and total degradation products of amlodipine besylate by liquid chromatography and liquid chromatography-mass spectrometry

An isocratic, reversed-phase liquid chromatographic method was applied for the investigation of the degradation products of amlodipine besylate under the stressed conditions in solution. Amlodipine besylate stock solutions were subjected to acid and alkali hydrolysis, chemical oxidation and...

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Bibliographic Details
Main Authors: Stoiljković Zora Ž., Jadranin Milka B., Đurić Svetlana Lj., Petrović Slobodan D., Ivić Avramov Milka L., Mijin Dušan Ž.
Format: Article
Language:English
Published: Association of the Chemical Engineers of Serbia 2014-01-01
Series:Chemical Industry and Chemical Engineering Quarterly
Subjects:
Online Access:http://www.doiserbia.nb.rs/img/doi/1451-9372/2014/1451-93721300011S.pdf