The Circadian <i>tau</i> Mutation in Casein Kinase 1 Is Part of a Larger Domain That Can Be Mutated to Shorten Circadian Period

The Circadian <i>tau</i> Mutation in Casein Kinase 1 Is Part of a Larger Domain That Can Be Mutated to Shorten Circadian Period

Drosophila Double-time (DBT) phosphorylates the circadian protein Period (PER). The period-altering mutation <i>tau</i>, identified in hamster casein kinase I (CKI&#949;) and created in Drosophila DBT, has been shown to shorten the circadian period in flies, as it does in hamsters. S...

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Bibliographic Details
Main Authors: Anandakrishnan Venkatesan, Jin-Yuan Fan, Samuel Bouyain, Jeffrey L. Price
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:International Journal of Molecular Sciences
Subjects:
circadian rhythms
PER protein
protein/protein interactions
protein phosphorylation
biological clocks
nuclear localization signal
phosphate recognition
Online Access:https://www.mdpi.com/1422-0067/20/4/813

Internet

https://www.mdpi.com/1422-0067/20/4/813

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