Factors Associated With Premature Ovarian Insufficiency in Young Women With Locally Advanced Rectal Cancer Treated With Pelvic Radiation Therapy

Purpose: Pelvic radiation therapy (RT) is standard of care for patients with locally advanced rectal cancer (LARC). Premature ovarian insufficiency (POI) in premenopausal women is a possible side effect. The purpose of our study was to evaluate factors associated with POI in women younger than 50 ye...

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Main Authors: Lara Hilal, MD, Andrea Cercek, MD, John Navilio, CMD, Meier Hsu, MS, Zhigang Zhang, PhD, Paul Brady, BS, Abraham J. Wu, MD, Marsha Reyngold, MD, PhD, John J. Cuaron, MD, Paul B. Romesser, MD, Melissa Zinovoy, MD, Maliha Nusrat, MD, MS, Emmanouil Pappou, MD, PhD, FACS, FASCRS, Maria LaGratta, MD, Julio Garcia-Aguilar, MD, PhD, Philip Paty, MD, Nadeem Abu-Rustum, MD, FACOG, FACS, Mario M. Leitao, MD, FACOG, FACS, Christopher H. Crane, MD, Carla Hajj, MD
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Advances in Radiation Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S2452109421001597