An adverse outcome pathway for lung surfactant function inhibition leading to decreased lung function

An adverse outcome pathway for lung surfactant function inhibition leading to decreased lung function

Inhaled substances, such as consumer products, chemicals at the workplace, and nanoparticles, can affect the lung function in several ways. In this paper, we explore the adverse outcome pathway (AOP) that starts when inhaled substances that reach the alveoli inhibit the function of the lung surfacta...

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Bibliographic Details
Main Authors: Emilie Da Silva, Ulla Vogel, Karin S. Hougaard, Jesus Pérez-Gil, Yi Y. Zuo, Jorid B. Sørli
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Current Research in Toxicology
Subjects:
Adverse outcome pathway
Inhalation
Lung surfactant
New approach methodology
Alternative method
Nanomaterials
Online Access:http://www.sciencedirect.com/science/article/pii/S2666027X21000220

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http://www.sciencedirect.com/science/article/pii/S2666027X21000220

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