The transcriptional response of mouse spleen B cells to IL-4: Comparison to the response of human peripheral blood B cells

The Th2 cytokine IL-4 triggers a signaling cascade which activates transcription by STAT6. The goals of the present study are to define the transcriptomic response of mouse spleen B cells (mSBC) to IL-4 used as single stimulus, its specificity compared to human peripheral blood B cells (hPBBC) and t...

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Bibliographic Details
Main Authors: Natalia Ruiz-Lafuente, Manuel Muro, Alfredo Minguela, Antonio Parrado
Format: Article
Language:English
Published: Elsevier 2018-12-01
Series:Biochemistry and Biophysics Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580818301183