Plasminogen activator inhibitor type 1 serum levels and 4G/5G gene polymorphism in morbidly obese Hispanic patients with non-alcoholic fatty liver disease(♦)(♦)This work was supported by grants from the Fondo Nacional de Ciencia y Tecnología de Chile (FONDECYT) #1110455 to M.A., #1100971 to M.A-L. and #1100020 to F.N.

Plasminogen activator inhibitor type 1 serum levels and 4G/5G gene polymorphism in morbidly obese Hispanic patients with non-alcoholic fatty liver disease(♦)(♦)This work was supported by grants from the Fondo Nacional de Ciencia y Tecnología de Chile (FONDECYT) #1110455 to M.A., #1100971 to M.A-L. and #1100020 to F.N.

Background. The plasminogen activator inhibitor type-1 (PAI-1) has been implicated in the regulation of fibrinolysis and extracellular matrix components. The single base pair guanine insertion/deletion polymorphism (4G/5G) within the promoter region of the PAI-1 gene influences PAI-1 synthesis and m...

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Main Authors: Alberto Espino, Andrea Villagrán, Valeska Vollrath, Paulina Hanckes, Roberto Salas, Andrea Farah, Nancy Solís, Margarita Pizarro, Alex Escalona, Camilo Boza, Gustavo Pérez, Gonzalo Carrasco, Oslando Padilla, Juan Francisco Miquel, Flavio Nervi, Norberto C. Chavez-Tapia, Juan Pablo Arab, Manuel Álvarez-Lobos, Marco Arrese, Arnoldo Riquelme
Format: Article
Language:English
Published: Elsevier 2011-10-01
Series:Annals of Hepatology
Subjects:
Plasminogen activator inhibitor type 1
Single nucleotide polymorphisms
Liver fibrosis
Non-alcoholic fatty liver disease
Steatosis
Online Access:http://www.sciencedirect.com/science/article/pii/S1665268119315182

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http://www.sciencedirect.com/science/article/pii/S1665268119315182

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