m6A modification of lncRNA PCAT6 promotes bone metastasis in prostate cancer through IGF2BP2‐mediated IGF1R mRNA stabilization

m6A modification of lncRNA PCAT6 promotes bone metastasis in prostate cancer through IGF2BP2‐mediated IGF1R mRNA stabilization

Abstract Background Bone metastasis is the leading cause of tumor‐related death in prostate cancer (PCa) patients. Long noncoding RNAs (lncRNAs) have been well documented to be involved in the progression of multiple cancers. Nevertheless, the role of lncRNAs in PCa bone metastasis remains largely u...

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Bibliographic Details
Main Authors: Chuandong Lang, Chi Yin, Kaiyuan Lin, Yue Li, Qing Yang, Zhengquan Wu, Hong Du, Dong Ren, Yuhu Dai, Xinsheng Peng
Format: Article
Language:English
Published: Wiley 2021-06-01
Series:Clinical and Translational Medicine
Subjects:
bone metastasis
IGF1R
IGF2BP2
PCAT6
prostate cancer
Online Access:https://doi.org/10.1002/ctm2.426

Internet

https://doi.org/10.1002/ctm2.426

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