Minimal residual disease monitoring via AML1-ETO breakpoint tracing in childhood acute myeloid leukemia

Minimal residual disease monitoring via AML1-ETO breakpoint tracing in childhood acute myeloid leukemia

Relapse of childhood AML1-ETO (AE) acute myeloid leukemia is the most common cause of treatment failure. Optimized minimal residual disease monitoring methods is required to prevent relapse. In this study, we used next-generation sequencing to identify the breakpoints in the fusion gene and the DNA-...

Full description

Bibliographic Details
Main Authors: Xiaoyan Chen, Suyu Zong, Meihui Yi, Chao Liu, Bingrui Wang, Yongjuan Duan, Xuelian Cheng, Min Ruan, Li Zhang, Yao Zou, Yumei Chen, Wenyu Yang, Ye Guo, Xiaojuan Chen, Tianyuan Hu, Tao Cheng, Xiaofan Zhu, Yingchi Zhang
Format: Article
Language:English
Published: Elsevier 2021-08-01
Series:Translational Oncology
Subjects:
Droplet digital PCR
Acute myeloid leukemia
AML1-ETO fusion gene
Online Access:http://www.sciencedirect.com/science/article/pii/S193652332100111X

Internet

http://www.sciencedirect.com/science/article/pii/S193652332100111X

Similar Items