Identification of cinnabarinic acid as a novel endogenous aryl hydrocarbon receptor ligand that drives IL-22 production.

Identification of cinnabarinic acid as a novel endogenous aryl hydrocarbon receptor ligand that drives IL-22 production.

The aryl hydrocarbon receptor (AHR) binds to environmental toxicants including synthetic halogenated aromatic hydrocarbons and is involved in a diverse array of biological processes. Recently, the AHR was shown to control host immunity by affecting the balance between inflammatory T cells that produ...

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Bibliographic Details
Main Authors: Margaret M Lowe, Jeff E Mold, Bittoo Kanwar, Yong Huang, Alexander Louie, Michael P Pollastri, Cuihua Wang, Gautam Patel, Diana G Franks, Jennifer Schlezinger, David H Sherr, Allen E Silverstone, Mark E Hahn, Joseph M McCune
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3912126?pdf=render

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http://europepmc.org/articles/PMC3912126?pdf=render

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