Triggering Receptors Expressed on Myeloid Cells 2 Promotes Corneal Resistance Against Pseudomonas aeruginosa by Inhibiting Caspase-1-Dependent Pyroptosis

Triggering Receptors Expressed on Myeloid Cells 2 Promotes Corneal Resistance Against Pseudomonas aeruginosa by Inhibiting Caspase-1-Dependent Pyroptosis

Triggering receptors expressed on myeloid cells 2 (TREM2) is a novel cell surface receptor and functions as an immunomodulatory receptor in infectious diseases. In this study, we investigated the function and regulatory mechanism of TREM2 in Pseudomonas aeruginosa (P. aeruginosa) keratitis. We found...

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Bibliographic Details
Main Authors: Wenting Qu, Yi Wang, Yongjian Wu, Yiting Liu, Kang Chen, Xi Liu, Zhengyu Zou, Xi Huang, Minhao Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Immunology
Subjects:
Pseudomonas aeruginosa
triggering receptors expressed on myeloid cells 2
corneal infection
pyroptosis
inflammation
bacterial killing
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01121/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.01121/full

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