Role of reactive oxygen species in bradykinin-induced proliferation of vascular smooth muscle cells

Role of reactive oxygen species in bradykinin-induced proliferation of vascular smooth muscle cells

In addition to the induction of cell proliferation and migration, bradykinin (BK) can increase c-fos mRNA expression, activate ERK 1/2 and generate reactive oxygen species (ROS) in vascular smooth muscle cells (VSMC). It is not known, however, whether BK can induce cellular proliferation and extrace...

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Bibliographic Details
Main Authors: VICTORIA VELARDE, PAULA M DE LA CERDA, CLAUDIA DUARTE, FRANCISCA ARANCIBIA, EDUARDO ABBOTT, ALEJANDRO GONZÁLEZ, FRANCESCA MORENO, AYAD A JAFFA
Format: Article
Language:English
Published: BMC 2004-01-01
Series:Biological Research
Subjects:
bradykinin, antioxidants
migration
signal transduction
reactive oxygen species
Online Access:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602004000300007

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http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602004000300007

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