Evolutionary-Conserved Allosteric Properties of Three Neuronal Calcium Sensor Proteins

Evolutionary-Conserved Allosteric Properties of Three Neuronal Calcium Sensor Proteins

Neuronal Calcium Sensors (NCS) are highly conserved proteins specifically expressed in neurons. Calcium (Ca2+)-binding to their EF-hand motifs results in a conformational change, which is crucial for the recognition of a specific target and the downstream biological process. Here we present a compre...

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Bibliographic Details
Main Authors: Valerio Marino, Daniele Dell'Orco
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Molecular Neuroscience
Subjects:
NCS1
recoverin
GCAP1
protein structure network
molecular dynamics
neuronal calcium sensors
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2019.00050/full

Internet

https://www.frontiersin.org/article/10.3389/fnmol.2019.00050/full

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