Evaluation of low-dose proton beam radiation efficiency in MIA PaCa-2 pancreatic cancer cell line vitality and H2AX formation

Evaluation of low-dose proton beam radiation efficiency in MIA PaCa-2 pancreatic cancer cell line vitality and H2AX formation

Background and objective: The aim of this study was to evaluate the efficiency of proton beam irradiation in pancreatic cancer cell line MIA PaCa-2 and its role in the cell cycle, apoptosis, and formation of histone γH2AX in different reparation times (72-h follow-up). Material and methods: The MIA...

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Bibliographic Details
Main Authors: Aušra Liubavičiūtė, Jan Aleksander Kraśko, Agata Mlynska, Jelena Lagzdina, Kęstutis Sužiedėlis, Vita Pašukonienė
Format: Article
Language:English
Published: MDPI AG 2015-11-01
Series:Medicina
Subjects:
Proton irradiation
MIA PaCa-2
Gamma H2AX
Non-homologous end joining
Double strand breaks
Online Access:http://www.sciencedirect.com/science/article/pii/S1010660X15000890

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http://www.sciencedirect.com/science/article/pii/S1010660X15000890

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