Awakening a latent carbon fixation cycle in Escherichia coli

Current efforts to establish synthetic carbon fixation in model heterotrophs rely on expression of heterologous enzymes. Here, the authors explore the presence and activity of a latent CO2-assimilation pathway in E. coli based only on endogenous enzymes and a reversible decarboxylase.

Bibliographic Details
Main Authors: Ari Satanowski, Beau Dronsella, Elad Noor, Bastian Vögeli, Hai He, Philipp Wichmann, Tobias J. Erb, Steffen N. Lindner, Arren Bar-Even
Format: Article
Language:English
Published: Nature Publishing Group 2020-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-19564-5