Both inflammatory and regulatory cytokine responses to malaria are blunted with increasing age in highly exposed children

Abstract Background Young children are at greatest risk for malaria-associated morbidity and mortality. The immune response of young children differs in fundamental ways from that of adults, and these differences likely contribute to the increased susceptibility of children to severe malaria and to...

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Bibliographic Details
Main Authors: Lila Farrington, Hilary Vance, John Rek, Mary Prahl, Prasanna Jagannathan, Agaba Katureebe, Emmanuel Arinaitwe, Moses R. Kamya, Grant Dorsey, Margaret E. Feeney
Format: Article
Language:English
Published: BMC 2017-12-01
Series:Malaria Journal
Subjects:
Age
Online Access:http://link.springer.com/article/10.1186/s12936-017-2148-6