Polycomb group protein Ezh2 regulates hepatic progenitor cell proliferation and differentiation in murine embryonic liver.

In embryonic liver, hepatic progenitor cells are actively proliferating and generate a fundamental cellular pool for establishing parenchymal components. However, the molecular basis for the expansion of the progenitors maintaining their immature state remains elusive. Polycomb group proteins regula...

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Bibliographic Details
Main Authors: Hiroyuki Koike, Rie Ouchi, Yasuharu Ueno, Susumu Nakata, Yuta Obana, Keisuke Sekine, Yun-Wen Zheng, Takanori Takebe, Kyoichi Isono, Haruhiko Koseki, Hideki Taniguchi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4143191?pdf=render