Constitutive Activation of Natural Killer Cells in Primary Biliary Cholangitis

Constitutive Activation of Natural Killer Cells in Primary Biliary Cholangitis

Natural killer (NK) cells are innate immune cells that interface with the adaptive immune system to generate a pro-inflammatory immune environment. Primary Biliary Cholangitis (PBC) is a hepatic autoimmune disorder with extrahepatic associations including systemic sclerosis, Sjogren's syndrome...

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Bibliographic Details
Main Authors: Theresa J. Hydes, Matthew D. Blunt, Jennifer Naftel, Andres F. Vallejo, Grégory Seumois, Alice Wang, Pandurangan Vijayanand, Marta E. Polak, Salim I. Khakoo
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Immunology
Subjects:
primary biliary cholangitis
natural killer cells
chemokine receptor 6 protein
human
interleukin-12
STAT4 transcription factor
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02633/full

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https://www.frontiersin.org/article/10.3389/fimmu.2019.02633/full

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