Transcriptomic biomarker pathways associated with death in HIV-infected patients with cryptococcal meningitis

Transcriptomic biomarker pathways associated with death in HIV-infected patients with cryptococcal meningitis

Abstract Background Cryptococcal meningitis (CM) is a major cause of death in HIV-infected patients in sub-Saharan Africa. Many CM patients experience cryptococcosis-associated immune reconstitution inflammatory syndrome (C-IRIS), which is often fatal. We sought to identify transcriptomic biomarker...

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Bibliographic Details
Main Authors: Irina Vlasova-St Louis, Abdu K. Musubire, David B. Meya, Henry W. Nabeta, Hesham Mohei, David R. Boulware, Paul R. Bohjanen
Format: Article
Language:English
Published: BMC 2021-04-01
Series:BMC Medical Genomics
Subjects:
Fatal immune reconstitution inflammatory syndrome
Transcriptomic biomarkers
AIDS/HIV
Cryptococcal meningitis IRIS
Online Access:https://doi.org/10.1186/s12920-021-00914-1

Internet

https://doi.org/10.1186/s12920-021-00914-1

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