Porcine RIG-I and MDA5 Signaling CARD Domains Exert Similar Antiviral Function Against Different Viruses

Porcine RIG-I and MDA5 Signaling CARD Domains Exert Similar Antiviral Function Against Different Viruses

The RIG-I-like receptors (RLRs) RIG-I and MDA5 play critical roles in sensing and fighting viral infections. Although RIG-I and MDA5 have similar molecular structures, these two receptors have distinct features during activation. Further, the signaling domains of the N terminal CARD domains (CARDs)...

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Bibliographic Details
Main Authors: Shuangjie Li, Qi Shao, Yuanyuan Zhu, Xingyu Ji, Jia Luo, Yulin Xu, Xueliang Liu, Wanglong Zheng, Nanhua Chen, François Meurens, Jianzhong Zhu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Microbiology
Subjects:
RLRs
porcine
CARD
signaling activity
antiviral function
transcriptome
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2021.677634/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2021.677634/full

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