Tumor Expression of Cyclin-Dependent Kinase 5 (Cdk5) Is a Prognostic Biomarker and Predicts Outcome of Oxaliplatin-Treated Metastatic Colorectal Cancer Patients

Tumor Expression of Cyclin-Dependent Kinase 5 (Cdk5) Is a Prognostic Biomarker and Predicts Outcome of Oxaliplatin-Treated Metastatic Colorectal Cancer Patients

In recent years, an increasing number of studies have shown that elevated expression of cyclin dependent kinase (Cdk5) contributes to the oncogenic initiation and progression of many types of cancers. In this study, we investigated the expression pattern of Cdk5 in colorectal cancer (CRC) cell lines...

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Bibliographic Details
Main Authors: Vicenç Ruiz de Porras, Sara Bystrup, Sara Cabrero-de las Heras, Eva Musulén, Luis Palomero, Maria Henar Alonso, Rocio Nieto, Diego Arango, Víctor Moreno, Cristina Queralt, José Luis Manzano, Laura Layos, Cristina Bugés, Eva Martinez-Balibrea
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Cancers
Subjects:
colorectal cancer
cyclin-dependent kinase 5 (cdk5)
prognostic and predictive biomarker
oxaliplatin
Online Access:https://www.mdpi.com/2072-6694/11/10/1540

Internet

https://www.mdpi.com/2072-6694/11/10/1540

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