A low molecular weight heparin inhibits experimental metastasis in mice independently of the endothelial glycocalyx.

A low molecular weight heparin inhibits experimental metastasis in mice independently of the endothelial glycocalyx.

BACKGROUND: Some low molecular weight heparins (LMWHs) prolong survival of cancer patients and inhibit experimental metastasis. The underlying mechanisms are still not clear but it has been suggested that LMWHs (at least in part) limit metastasis by preventing cancer cell-induced destruction of the...

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Bibliographic Details
Main Authors: Geerte L Van Sluis, Max Nieuwdorp, Pieter W Kamphuisen, Johan van der Vlag, Cornelis J F Van Noorden, C Arnold Spek
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2888573?pdf=render

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http://europepmc.org/articles/PMC2888573?pdf=render

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